Blood plasma:
plasma is that part of extracellular fluid which is identical to interstitial fluid but it contains 7% proteins while interstitial fluid contains 2% proteins.
Volume
3300 ml
Difference between plasma and interstitial fluid:
both plasma and interstitial fluid are part of extracellular fluid and are almost identical to each other except for Plasma contains 7% proteins while interstitial fluid contains 2% proteins.
Difference between serum and plasma:
Fuid part of blood which expresses out after clotting due to clot retraction, is called serum. serum resembles plasma but it has no fibrinogen and other clotting factor as it is formed after clotting.
Difference between human and animal blood:
Human blood forms hemin crystals, while animals blood do not.
Origin of Plasma proteins:
all plasma proteins are formed in liver except Gamma globulin which is formed in reticuloendothelial system, plasma cells, and lymphocytes.
Function of Plasma proteins
1. essential for blood clotting, eg fibrinogen and prothrombin.
2) maintain colloid Osmotic pressure of blood; thus help in fluid distribution between blood and tissue.
3) maintain viscosity and blood pressure
4) Regulate erythrocyte sedimentation rate. increased fibrinogen causes increase erythrocyte sedimentation rate.
5) Act as buffer; thus maintain acid-base balance.
6) Act as protein reserve; thus provide nutrition during starvation and in that inadequate protein diet.
7) Help carbon dioxide carriage by forming carbamino proteins.
8) Form trephones; leukocytes prepare substances called trephones from plasma proteins, which are essential for nourishment of tissue cells grown in culture.
9) antibodies (Gamma-globulins combat disease causing organisms.
10) transport substances in blood; e.g. hormones, enzymes, iron (transferrin) and copper (ceruloplasmin) are transported by globulin.
Composition of blood
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