MINISTRY OF DEFENCE

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  MINISTRY OF DEFENCE. Establishment Of National University In Islamabad Total position. 29 Domicile , All over Pakistan    Qualification  intermediate to bachelor positions . Project Engineer(Civil) account Officer  supervisor assistant office boy     How to apply.   Apply online through the link https://www.fgei-cg.gov.pk/nup-rec.php   Last date to apply  02 April 2023. No TA/DA Fo Interview 
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Action Of Enzyme (Mechanism Of Action of Enzyme)

Action Of Enzyme (Mechanism Of Action of Enzyme)


The specificity of enzyme is very important in the metabolism of living system its catalytic activity is restricted to a reaction or a group of related reaction.
For example: Urease is specific for urea substrate.
 Enzymes combined with their substrate and form Complex, called enzyme substrate Complex.
Enzymes have an active site with which a substrate molecule is attached.

The Action Of Enzyme depends upon the structure of enzyme.
 It has three dimensional structure.
It has an active site which is of a particular size and shape.
This active site is attached with Substrate.

 Two theories have been proposed about the action of enzyme.

 I) Key Lock Theory:
Key and lock theory of Enzyme

 This theory has proposed by Fischer in 1898, and it has improved by Paul filder and D.D woods.

According to this theory the enzyme is attached with specific substrate by its active site to form an association this association is like a lock and key Association.
 It helps in the catalytic action. Sometimes other molecules or substrate are connected with active site, but there is no Bond formation and no chemical reaction.


ii) Induced Fit Model Theory
 This theory is proposed by koshland in 1959. According to this theory when enzyme combines with the substrate, some changes occur in the substrate of enzyme, due to this change the enzyme performs catalytic activity in more effective manner.

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